genetics
![Brian Piercy](data:image/svg+xml;utf8,<svg xmlns="http://www.w3.org/2000/svg" viewBox="0 0 24 24" fill="%230A66C2"><path d="M20.447 20.452H16.89v-5.569c0-1.328-.027-3.037-1.852-3.037-1.853 0-2.136 1.445-2.136 2.939v5.667H9.351V9h3.414v1.561h.046c.477-.9 1.637-1.85 3.37-1.85 3.601 0 4.267 2.37 4.267 5.455v6.286zM5.337 7.433a1.982 1.982 0 1 1 0-3.964 1.982 1.982 0 0 1 0 3.964zm1.782 13.019H3.555V9h3.564v11.452zM22.225 0H1.771C.792 0 0 .774 0 1.729v20.542C0 23.227.792 24 1.771 24h20.451C23.2 24 24 23.227 24 22.271V1.729C24 .774 23.2 0 22.222 0h.003z"/></svg>)
In the first episode of the new season of ‘The Joy of Why,’ Nobel Laureate Jennifer Doudna discusses how she discovered CRISPR’s genome-editing power, the breakthroughs and hurdles during its explosive growth, and what lies ahead for this groundbreaking technology.
How resistance to growth hormone creates extraordinary disease resistance
In the 1940s, scientists made a discovery now fundamental to biology: genes are encoded in DNA. The story involves bacteria, dead mice, and a kitchen cream separator.
The genetic founder event that shaped a civilisation
Everyone’s DNA keeps mutating. Could correcting those errors lead to longevity?
Understanding the genetics of circulating viruses will determine if the U.S. loses measles elimination status this year.
The genetic disorder that turns the body into an iron trap
While some bacteriophages play vital roles in laboratory research, others are bent on sabotage.
A step-by-step guide to making de novo binders.
How to “read” nucleic acids, from Sanger to nanopores.
The secrets to extending human lifespans might lie in the animals that can already live for centuries.
This year, gene-editing technology was customized to fix mutations in a single patient’s genes for the first time.
The newly described microbe represents a world of parasitic, intercellular biodiversity only beginning to be revealed by genome sequencing.
Vaccines based on mRNA can be tailored to target a cancer patient’s unique tumor mutations. But crumbling support for cancer and mRNA vaccine research has endangered this promising therapy
Can a ‘molecular crowbar’ fight pancreatic cancer?
A new study looked into the axolotl’s freakish regenerative talents, hoping to uncover secrets that could revolutionize human medicine.
A selected encyclopedia of major gene-editing systems, together with illustrated diagrams.
In one tiny town, more than a dozen people were diagnosed with the rare neurodegenerative disease ALS. Why?
Proteins are often visualized as cascades of curled ribbons and twisted strings, which both reveal and conceal the mess of atoms that make up these impossibly complex molecules.
No human genome has ever been read in its entirety before. This year, scientists expect to pass that milestone for the first time.
Racial categories are crude maps imposed on human biological variation. How do scientists square them with genetics?
New way of altering DNA is used to engineer an "exciting", experimental therapy for a 13-year-old girl.
What do infectious diseases, T-cells, tomatoes, heart failure, sickle cell anemia and sorghum harvests have in common?
No need to worry about getting stuck in local minima anymore
Real-time pathogen detection, microbiome characterization and outbreak detection for researchers
Genetic Science Learning Center
Training an end-to-end differentiable, self-organising cellular automata model of morphogenesis, able to both grow and regenerate specific patterns.
How one nonprofit’s mailroom is making tinkering with genomes as easy as shopping at Amazon.
Researchers have developed “prime editing,” a true search-and-replace function for DNA.
Sébastien Calvignac-Spencer searches museum jars for genetic traces of flu, measles and other viruses. Their evolutionary stories can help treat modern outbreaks and prepare for future ones.