Dogs, devils, clams and catfish: When cancer is contagious
In a handful of animals, tumors can be transmitted like infectious diseases or parasites, defying science’s tidy definitions
genetics
The Family Plan - The Atavist Magazine
When a little girl in Iowa was diagnosed with a rare incurable disease, her parents and their community came together to help her. They wound up making medical history.
The Evolving Quest to Build Life in a Lab
Scientists want to create cells from scratch, to unveil life's origins or provide specialized functions. Are they close?
The Next Gene-Editing Technology May Also Be the Oldest
Scientists have discovered a powerful gene-targeting system in viruses. Billions of years old, VIPR seems to predate CRISPR and may be even more powerful.
The Bone-Marrow-Transplant Revolution
Finding a matched donor has always been the major challenge. A drug has solved that problem.
The kill switch for harmful genes - Works in Progress Magazine
What if instead of editing a gene, or blocking the protein it produces, you could simply switch it off?
Extreme evolution: The animals evolving at super speed to survive
Humans have become one of the world's greatest evolutionary forces. To survive our cities, animals from urban foxes to glass-climbing lizards are responding with extreme adaptation.
Exclusive: Death of girl in Chinese gene-editing trial was never made public
Parents want accountability after study went disastrously wrong, Science and Retraction Watch investigation reveals
A strange transmissible cancer is spreading through the catfish in this lake
For more than a decade, there's been something fishy going on in a lake that straddles Vermont and the province of Quebec. It involves cancer, a kind of catfish, and — possibly — clues about how tumors metastasize.
What’s the Future of Gene Editing? | Quanta Magazine
In the first episode of the new season of ‘The Joy of Why,’ Nobel Laureate Jennifer Doudna discusses how she discovered CRISPR’s genome-editing power, the breakthroughs and hurdles during its explosive growth, and what lies ahead for this groundbreaking technology.
Laron syndrome: The dwarfism that protects against cancer and diabetes
How resistance to growth hormone creates extraordinary disease resistance
How we learned what genes are made of
In the 1940s, scientists made a discovery now fundamental to biology: genes are encoded in DNA. The story involves bacteria, dead mice, and a kitchen cream separator.
The Ashkenazi bottleneck: How 350 people became millions
The genetic founder event that shaped a civilisation
The DNA Fix for Aging
Everyone’s DNA keeps mutating. Could correcting those errors lead to longevity?
Inside the Effort to Sequence a Thousand Measles Genomes
Understanding the genetics of circulating viruses will determine if the U.S. loses measles elimination status this year.
The Celtic Curse: How a Bronze Age mutation became Ireland’s deadly inheritance
The genetic disorder that turns the body into an iron trap
How Φ80 Infiltrates Research Labs
While some bacteriophages play vital roles in laboratory research, others are bent on sabotage.
How to Design Antibodies
A step-by-step guide to making de novo binders.
A Visual Guide to DNA Sequencing
How to “read” nucleic acids, from Sanger to nanopores.
Learning about longevity from long-lived animals
The secrets to extending human lifespans might lie in the animals that can already live for centuries.
The Rarest of All Diseases Are Becoming Treatable
This year, gene-editing technology was customized to fix mutations in a single patient’s genes for the first time.
A Cell So Minimal That It Challenges Definitions of Life | Quanta Magazine
The newly described microbe represents a world of parasitic, intercellular biodiversity only beginning to be revealed by genome sequencing.
Personalized mRNA Vaccines Will Revolutionize Cancer Treatment—If Federal Funding Cuts Don’t Doom Them
Vaccines based on mRNA can be tailored to target a cancer patient’s unique tumor mutations. But crumbling support for cancer and mRNA vaccine research has endangered this promising therapy
Can a 'molecular crowbar' fight pancreatic cancer? - Futurity
Can a ‘molecular crowbar’ fight pancreatic cancer?
Axolotls Can Regenerate Limbs, and Scientists Are Finally Learning How
A new study looked into the axolotl’s freakish regenerative talents, hoping to uncover secrets that could revolutionize human medicine.
A Visual Guide to Genome Editors
A selected encyclopedia of major gene-editing systems, together with illustrated diagrams.
Was a Mushroom Behind an ALS Outbreak in the Alps?
In one tiny town, more than a dozen people were diagnosed with the rare neurodegenerative disease ALS. Why?
How Colorful Ribbon Diagrams Became the Face of Proteins
Proteins are often visualized as cascades of curled ribbons and twisted strings, which both reveal and conceal the mess of atoms that make up these impossibly complex molecules.
Why the human genome was never completed
No human genome has ever been read in its entirety before. This year, scientists expect to pass that milestone for the first time.
The Complicated Quest to Decipher Human Difference
Racial categories are crude maps imposed on human biological variation. How do scientists square them with genetics?
Base editing: Revolutionary therapy clears girl's incurable cancer - BBC Ne
New way of altering DNA is used to engineer an "exciting", experimental therapy for a 13-year-old girl.
The Many Uses of CRISPR: Scientists Tell All (Published 2022)
What do infectious diseases, T-cells, tomatoes, heart failure, sickle cell anemia and sorghum harvests have in common?
Complete Step-by-step Genetic Algorithm from Scratch for Global Optimization
No need to worry about getting stuck in local minima anymore
IDseq
Real-time pathogen detection, microbiome characterization and outbreak detection for researchers
http://libros.metabiblioteca.org:8080/bitstream/001/184/4/978-1-4092-0073-4.pdf
Learn Genetics
Genetic Science Learning Center
Growing Neural Cellular Automata
Training an end-to-end differentiable, self-organising cellular automata model of morphogenesis, able to both grow and regenerate specific patterns.
The Scientific Swap Meet Behind the Gene-Editing Boom
How one nonprofit’s mailroom is making tinkering with genomes as easy as shopping at Amazon.
The newest gene editor radically improves on CRISPR
Researchers have developed “prime editing,” a true search-and-replace function for DNA.
The Viral Paleontologist Who Unearths Pathogens’ Deep Histories
Sébastien Calvignac-Spencer searches museum jars for genetic traces of flu, measles and other viruses. Their evolutionary stories can help treat modern outbreaks and prepare for future ones.